1: in tetrahydrofuran; diethyl ether; tert-butyl methyl ether
T=17 - 23°C; Inert atmosphere;
2: With ammonium chloride in tetrahydrofuran; diethyl ether; tert-butyl methyl ether; water
参考文献
SANOFI-AVENTIS; LEE, George E.; SHRIMP II, Frederick L.; WEIBERTH, Franz J.
Patent: WO2010/107969 A1, 2010 ;
Location in patent: Page/Page column 6-8 ;