2,4-二甲氧基-6-甲基嘧啶合成路线 （共 21 条）
反应条件
trichlorophosphate
Erwaermen des Reaktionsprodukts mit Natriummethylat in Methanol;
参考文献
Ochiai; Yamanaka
Pharmaceutical Bulletin, 1955 , vol. 3, p. 175,176
参考文献
Yamanaka
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 505,508
参考文献
Yamanaka
Chemical and Pharmaceutical Bulletin, 1958 , vol. 6, p. 633,634
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 505,507
反应条件
1,4-dioxane; methanol
参考文献
Andrisano
Bollettino Scientifico della Facolta di Chimica Industriale di Bologna, 1944 , vol. 5, p. 48,51
参考文献
Yamanaka
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 505,508
参考文献
Yamanaka
Chemical and Pharmaceutical Bulletin, 1958 , vol. 6, p. 633,634
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 505,507
反应条件
T=300 - 350°C; Unter Druck;
参考文献
Chi; Ling
Scientia Sinica (English Edition), 1955 , vol. 4, p. 119,125
反应条件
1: With acetic acid
0.333333 h; Heating;
2: With N-bromosuccinmide
3 h; Heating; Further stages.;
参考文献
Prekupec, Svjetlana; Makuc, Damjan; Plavec, Janez; Suman, Lidija; Kralj, Marijeta; Pavelic, Kresimir; Balzarini, Jan; De Clercq, Erik; Mintas, Mladen; Raic-Malic, Silvana
Journal of Medicinal Chemistry, 2007 , vol. 50, # 13 p. 3037 - 3045
参考文献
Kristafor, Svjetlana; Kraljevic, Tatjana Gazivoda; Makuc, Damjan; Plavec, Janez; Suman, Lidija; Kralj, Marijeta; Raic-Malic, Silvana
Molecules, 2009 , vol. 14, # 12 p. 4866 - 4879
反应条件
sodium carbonate in acetonitrile
36 h; Heating;
参考文献
Bhat, Sunita
Collection of Czechoslovak Chemical Communications, 1994 , vol. 59, # 3 p. 683 - 690
