2-氨基-4-(4-氟苯基)噻唑合成路线 （共 10 条）
参考文献
Siddiqui, Hamid Latif; Iqbal, Amjid; Ahmad, Saeed; Weaver, George W.
Molecules, 2006 , vol. 11, # 2-3 p. 206 - 211
反应条件
nBu4NPF6 in methanol T=20°C; 0.216667 h;
参考文献
Kocabas, Erdal; Sariguney, Ahmet Burak; Coskun, Ahmet
Heterocycles, 2010 , vol. 81, # 12 p. 2849 - 2854
反应条件
copper(II) bis(trifluoromethanesulfonate) in 1,2-dichloro-ethane T=80°C; 2.5 h;
参考文献
Yadav; Reddy, B.V. Subba; Rao, Y. Gopala; Narsaiah
Tetrahedron Letters, 2008 , vol. 49, # 15 p. 2381 - 2383
反应条件
sodium carbonate in poly(ethylene glycol-400) T=20°C;
参考文献
Lin, Pei-Ying; Hou, Rei-Sheu; Wang, Huey-Min; Kang, Iou-Jiun; Chen, Ling-Ching
Journal of the Chinese Chemical Society, 2009 , vol. 56, # 3 p. 455 - 458
参考文献
Tetrahedron Letters, , vol. 53, # 30 p. 3835 - 3838
反应条件
1-methyl-1H-imidazole in water; isopropyl alcohol T=20°C; 1.2 h;
参考文献
Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5265 - 5269
反应条件
1: Br2 / CHCl3 / 0.5 h / Heating 2: ethanol / 3 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 20 p. 3581 - 3584
参考文献
Walchshofer; Minjat; Tinland; et al.
European Journal of Medicinal Chemistry, 1986 , vol. 21, # 1 p. 59 - 64
反应条件
1: N-bromosuccinmide; water; β-cyclodextrin / 0.17 h / 70 °C 2: water / 70 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 53, # 30 p. 3835 - 3838
反应条件
in benzene
3 h; Heating;
参考文献
XENON PHARMACEUTICALS INC.
Patent: WO2008/101029 A2, 2008 ;
Location in patent: Page/Page column 78 ;
WO 2008/101029 A2
