N,N'-二-叔丁氧羰基-(L)-胱氨酸二甲酯合成路线 (共 19 条)
反应条件
1: 97 percent / thionyl chloride / Heating
2: 77 percent / aq. NaOH / dioxane / 24 h / 20 °C
View Scheme
参考文献
Busnel, Olivier; Carreaux, Francois; Carboni, Bertrand; Pethe, Stephanie; Goff, Sandrine Vadon-Le; Mansuy, Daniel; Boucher, Jean-Luc
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 7 p. 2373 - 2379
反应条件
TEA in N,N-dimethyl-formamide
T=60°C; 0.5 h; Yield given;
参考文献
McNulty; Still
Synthetic Communications, 1992 , vol. 22, # 7 p. 979 - 985
反应条件
1: 66 percent / aq. NaOH / dioxane / 0 - 20 °C
2: diethyl ether
View Scheme
参考文献
Chaume, Gregory; Kuligowski, Carine; Bezzenine-Laffolee, Sophie; Ricard, Louis; Pancrazi, Ange; Ardisson, Janick
Synthesis, 2004 , # 18 p. 3029 - 3036
反应条件
1: 85 percent / K2CO3 / dimethylformamide
2: pyridine
3: 81 percent / (BnNEt3)2MoS4 / acetonitrile / 28 °C
View Scheme
参考文献
Bhat, Ramakrishna G.; Porhiel, Emmanuel; Saravanan, Vadivelu; Chandrasekaran, Srinivasan
Tetrahedron Letters, 2003 , vol. 44, # 28 p. 5251 - 5253
反应条件
1: pyridine
2: 81 percent / (BnNEt3)2MoS4 / acetonitrile / 28 °C
View Scheme
参考文献
Bhat, Ramakrishna G.; Porhiel, Emmanuel; Saravanan, Vadivelu; Chandrasekaran, Srinivasan
Tetrahedron Letters, 2003 , vol. 44, # 28 p. 5251 - 5253
反应条件
1: 83 percent / triethylamine / H2O; dioxane / 3 h
2: 77 percent
3: 75 percent / tris(4-bromophenyl)ammoniumyl stibnate, NaHCO3 / acetonitrile / 1 h
View Scheme
参考文献
Platen, Martin; Steckhan, Eberhard
Liebigs Annalen der Chemie, 1984 , # 9 p. 1563 - 1576
反应条件
1: 77 percent
2: 75 percent / tris(4-bromophenyl)ammoniumyl stibnate, NaHCO3 / acetonitrile / 1 h
View Scheme
参考文献
Platen, Martin; Steckhan, Eberhard
Liebigs Annalen der Chemie, 1984 , # 9 p. 1563 - 1576
反应条件
iodine; hydrazine hydrate
1.) MeOH, 0 deg C to RT, 2 h, 2.) MeOH, RT, 2 h; Yield given. Multistep reaction;
参考文献
Gong, Young-Dae; Iwasawa, Nobuharu
Chemistry Letters, 1994 , # 11 p. 2139 - 2142
参考文献
Chaume, Gregory; Kuligowski, Carine; Bezzenine-Laffolee, Sophie; Ricard, Louis; Pancrazi, Ange; Ardisson, Janick
Synthesis, 2004 , # 18 p. 3029 - 3036