3-[6-[[4-(三氟甲氧基)苯基]氨基]-4-嘧啶基]苯甲酰胺合成路线 (共 3 条)
反应条件
DIEA; triphenylphosphine in ethanol; sodium carbonate; acetonitrile
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in water; acetonitrile T=90°C; 7 h; Inert atmosphere;
参考文献
Schneider, Ralf; Becker, Christian; Simard, Jeffrey R.; Getlik, Matthaeus; Bohlke, Nina; Janning, Petra; Rauh, Daniel
Journal of the American Chemical Society, 2012 , vol. 134, # 22 p. 9138 - 9141
反应条件
1: N-ethyl-N,N-diisopropylamine / ethanol / 4 h / Reflux 2: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; acetonitrile / 7 h / 90 °C / Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 134, # 22 p. 9138 - 9141