Nelumol A; (2E)-3-[4-[[(2E)-3,7-二甲基-2,6-辛二烯-1-基]氧基]-3,5-二甲氧基苯基]-2-丙烯-1-醇合成路线 （共 8 条）
反应条件
diisobutylaluminium hydride in diethyl ether; hexane
T=-78°C; 0.5 h;
参考文献
Zhao, Yu; Hao, Xiaojiang; Lu, Wei; Cai, Junchao; Yu, Hong; Sevenet, Thierry; Gueritte, Francoise
Journal of Natural Products, 2002 , vol. 65, # 6 p. 902 - 908
反应条件
lithium aluminium tetrahydride in diethyl ether
T=0°C; 1 h;
参考文献
Zhao, Yu; Hao, Xiaojiang; Lu, Wei; Cai, Junchao; Yu, Hong; Sevenet, Thierry; Gueritte, Francoise
Journal of Natural Products, 2002 , vol. 65, # 6 p. 902 - 908
反应条件
sodium tetrahydroborate in ethanol; water
T=20°C; 0.5 h;
参考文献
Bruyre, Celine; Genovese, Salvatore; Lallemand, Benjamin; Ionescu-Motatu, Alexandra; Curini, Massimo; Kiss, Robert; Epifano, Francesco
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4174 - 4179
反应条件
1: 50 percent / Ph3P; DEAD / tetrahydrofuran / 24 h / 20 °C
2: 86 percent / DIBAH / diethyl ether; hexane / 0.5 h / -78 °C
View Scheme
参考文献
Zhao, Yu; Hao, Xiaojiang; Lu, Wei; Cai, Junchao; Yu, Hong; Sevenet, Thierry; Gueritte, Francoise
Journal of Natural Products, 2002 , vol. 65, # 6 p. 902 - 908
反应条件
1: 98 percent / H2SO4 / 2 h / Heating
2: 50 percent / Ph3P; DEAD / tetrahydrofuran / 24 h / 20 °C
3: 86 percent / DIBAH / diethyl ether; hexane / 0.5 h / -78 °C
View Scheme
参考文献
Zhao, Yu; Hao, Xiaojiang; Lu, Wei; Cai, Junchao; Yu, Hong; Sevenet, Thierry; Gueritte, Francoise
Journal of Natural Products, 2002 , vol. 65, # 6 p. 902 - 908
反应条件
1: 86 percent / pyridine; piperidine / 4 h / 120 °C
2: 80 percent / LAH / diethyl ether / 1 h / 0 °C
View Scheme
参考文献
Zhao, Yu; Hao, Xiaojiang; Lu, Wei; Cai, Junchao; Yu, Hong; Sevenet, Thierry; Gueritte, Francoise
Journal of Natural Products, 2002 , vol. 65, # 6 p. 902 - 908
反应条件
1: 86 percent / PCC / CH2Cl2 / 5 h / 0 °C
2: 86 percent / pyridine; piperidine / 4 h / 120 °C
3: 80 percent / LAH / diethyl ether / 1 h / 0 °C
View Scheme
参考文献
Zhao, Yu; Hao, Xiaojiang; Lu, Wei; Cai, Junchao; Yu, Hong; Sevenet, Thierry; Gueritte, Francoise
Journal of Natural Products, 2002 , vol. 65, # 6 p. 902 - 908
反应条件
1: 90 percent / LAH / diethyl ether / 0.17 h / 0 °C
2: 86 percent / PCC / CH2Cl2 / 5 h / 0 °C
3: 86 percent / pyridine; piperidine / 4 h / 120 °C
4: 80 percent / LAH / diethyl ether / 1 h / 0 °C
View Scheme
参考文献
Zhao, Yu; Hao, Xiaojiang; Lu, Wei; Cai, Junchao; Yu, Hong; Sevenet, Thierry; Gueritte, Francoise
Journal of Natural Products, 2002 , vol. 65, # 6 p. 902 - 908
