2,3-二氢-5-甲基-7-三氟甲基-1H-1,4-二氮杂卓合成路线 （共 8 条）
反应条件
diazoacetic acid ethyl ester
T=100 - 120°C; 10 h;
参考文献
Skryabina, Z. E.; Burgart, Ya. V.; Saloutin, V. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1991 , vol. 40, # 4.2 p. 788 - 794
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1991 , # 4 p. 890 - 896
反应条件
EDA*2HClO4 in chloroform
2 h; Heating;
参考文献
Saloutin, V. I.; Skryabina, Z. E.; Burgart, Y. V.
Journal of Fluorine Chemistry, 1992 , vol. 56, # 3 p. 325 - 334
反应条件
in chloroform
2 h; Heating;
参考文献
Saloutin, V. I.; Skryabina, Z. E.; Burgart, Y. V.
Journal of Fluorine Chemistry, 1992 , vol. 56, # 3 p. 325 - 334
反应条件
in methanol
8 h; Heating;
参考文献
Burgart, Ya. V.; Skryabina, Z. E.; Saloutin, V. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1991 , vol. 40, # 9.2 p. 1849 - 1853
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1991 , # 9 p. 2088 - 2092
反应条件
T=20°C; Cyclization; elimination;
参考文献
Sosnovskikh; Mel'nikov
Russian Chemical Bulletin, 1999 , vol. 48, # 5 p. 975 - 978
反应条件
Ambient temperature;
参考文献
Sosnovskikh; Mel'nikov; Kovaleva
Russian Chemical Bulletin, 1998 , vol. 47, # 11 p. 2234 - 2237
反应条件
Ambient temperature;
参考文献
Sosnovskikh; Mel'nikov; Kovaleva
Russian Chemical Bulletin, 1998 , vol. 47, # 11 p. 2234 - 2237
反应条件
potassium hydroxide
1.) 100 - 120 deg C, 10 h, 2.) ethanol, pH 10 - 11; Yield given. Multistep reaction;
参考文献
Saloutin, V. I.; Skryabina, Z. E.; Burgart, Y. V.
Journal of Fluorine Chemistry, 1992 , vol. 56, # 3 p. 325 - 334
