ammonia in methanol 4 h; Ambient temperature;

1: POCl3 / various solvent(s) / 16 h / 4 - 7 °C 2: Et3N / 1,2-dimethoxy-ethane; various solvent(s) / 42 h / 4 - 7 °C 3: 57 percent / NH3 / methanol / 4 h / Ambient temperature View Scheme

1: Et3N / 1,2-dimethoxy-ethane; various solvent(s) / 42 h / 4 - 7 °C 2: 57 percent / NH3 / methanol / 4 h / Ambient temperature View Scheme