sodium hexamethyldisilazane in tetrahydrofuran; toluene
T=0 - 20°C;
参考文献
Klapars, Artis; Waldman, Jacob H.; Campos, Kevin R.; Jensen, Mark S.; McLaughlin, Mark; Chung, John Y. L.; Cvetovich, Raymond J.; Chen, Cheng-Yi
Journal of Organic Chemistry, 2005 , vol. 70, # 24 p. 10186 - 10189
UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE; MOORE, Bob, M., II; GURLEY, Steven; MUSTAFA, Suni
Patent: WO2011/22692 A2, 2011 ;
Location in patent: Page/Page column 11; 19 ;
WO 2011/022692 A2
1: iso-butyronitrile With lithium diisopropyl amide in tetrahydrofuran; hexane
T=-78°C; 0.333333 h;
2: 4-bromo-but-1-ene in tetrahydrofuran
T=-78 - 20°C;
参考文献
Burrell, Adam J. M.; Coldham, Iain; Watson, Luke; Oram, Niall; Pilgram, Christopher D.; Martin, Nathaniel G.
Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2290 - 2300
