N-(3-羟丙基)三氟乙酰胺合成路线 （共 10 条）
反应条件
hydrogenchloride in diethyl ether 3 - 11 h; Reflux;
参考文献
Lobanova; Stankevich; Kukharev
Russian Journal of Organic Chemistry, 2012 , vol. 48, # 10 p. 1289 - 1296
Zh. Org. Khim., 2012 , vol. 48, # 10 p. 1295 - 1301,7
反应条件
hydrogenchloride in diethyl ether 3 - 11 h; Reflux;
参考文献
Russian Journal of Organic Chemistry, , vol. 48, # 10 p. 1289 - 1296
Zh. Org. Khim., , vol. 48, # 10 p. 1295 - 1301,7
反应条件
T=0°C; Neat (no solvent);
参考文献
He, Tian; Gao, Wen-Chao; Wang, Wei-Kun; Zhang, Chi
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 5 p. 1113 - 1118
参考文献
Fliri, Anton Franz Joseph; Butler, Todd William; Gallaschun, Randall James
Patent: US2002/52355 A1, 2002 ;
US 20020052355 A1
反应条件
in 1,4-dioxane
3 h; Heating;
参考文献
Svirskaya, Polina I.; Leznoff, Clifford C.; Steinman, Martin
Journal of Organic Chemistry, 1987 , vol. 52, # 7 p. 1362 - 1364
反应条件
in dichloromethane
T=20°C; 0.5 h;
参考文献
Zanatta, Nilo; Wouters, Ana D.; Fantinel, Leonardo; Da Silva, Fabio M.; Barichello, Rosemario; Da Silva, Pedro E. A.; Ramos, Daniela F.; Bonacorso, Helio G.; Martins, Marcos A. P.
Synlett, 2009 , # 5 p. 755 - 758
参考文献
Barton, Derek H. R.; Fekih, Abdelwaheb; Lusinchi, Xavier
Bulletin de la Societe Chimique de France, 1988 , # 4 p. 681 - 687
参考文献
Lobanova; Stankevich; Kukharev
Russian Journal of Organic Chemistry, 2012 , vol. 48, # 10 p. 1289 - 1296
Zh. Org. Khim., 2012 , vol. 48, # 10 p. 1295 - 1301,7
反应条件
1: 63 percent / pyridine / acetonitrile / 3 h / 0 °C
2: 71 percent / NaI / acetone / 6 h / 20 °C
View Scheme
参考文献
Ikeda, Hisafumi; Fuji, Kaoru; Tanaka, Kiyoshi; Iso, Yasuyoshi; Yoneda, Fumio
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 10 p. 1455 - 1463
反应条件
hydrogenchloride in diethyl ether
3 - 11 h; Reflux;
参考文献
Lobanova; Stankevich; Kukharev
Russian Journal of Organic Chemistry, 2012 , vol. 48, # 10 p. 1289 - 1296
Zh. Org. Khim., 2012 , vol. 48, # 10 p. 1295 - 1301,7
