[1-[(E)-4-丁氧基丁-2-烯基]-4-苯基哌啶-4-基]丙酸酯盐酸盐合成路线 （共 4 条）
反应条件
hydrogen; Lindlar's catalyst in ethanol
T=21°C; 0.116667 h;
参考文献
Praliev, K. D.; Belikova, N. A.; Sokolov, D. V.; Kurilenko, V. M.; Khilenko, Zh. N.; Moiseeva, L. M.
Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 12 p. 850 - 853
Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 12 p. 32 - 35
反应条件
1: 82.4 percent / CuCl / dioxane / 4 h / 100 °C
2: propionic acid / 3.5 h / 95 °C
3: HCl / diethyl ether / 0 °C
4: 93.4 percent / H2 / 5percent Pd/CaCO3 / ethanol / 0.12 h / 21 °C
View Scheme
参考文献
Praliev, K. D.; Belikova, N. A.; Sokolov, D. V.; Kurilenko, V. M.; Khilenko, Zh. N.; Moiseeva, L. M.
Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 12 p. 850 - 853
Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 12 p. 32 - 35
反应条件
1: propionic acid / 3.5 h / 95 °C
2: HCl / diethyl ether / 0 °C
3: 93.4 percent / H2 / 5percent Pd/CaCO3 / ethanol / 0.12 h / 21 °C
View Scheme
参考文献
Praliev, K. D.; Belikova, N. A.; Sokolov, D. V.; Kurilenko, V. M.; Khilenko, Zh. N.; Moiseeva, L. M.
Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 12 p. 850 - 853
Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 12 p. 32 - 35
反应条件
1: HCl / diethyl ether / 0 °C
2: 93.4 percent / H2 / 5percent Pd/CaCO3 / ethanol / 0.12 h / 21 °C
View Scheme
参考文献
Praliev, K. D.; Belikova, N. A.; Sokolov, D. V.; Kurilenko, V. M.; Khilenko, Zh. N.; Moiseeva, L. M.
Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 12 p. 850 - 853
Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 12 p. 32 - 35
