2-(氯甲基)-4-甲基嘧啶合成路线 (共 2 条)
反应条件
thionyl chloride in dichloromethane 2 h; Inert atmosphereReflux;
参考文献
WO2013/142269 A1, ;
Paragraph 0628; 0629 ;
反应条件
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; triethylamine / acetonitrile / 20 - 100 °C / |Inert atmosphere 2: sodium tetrahydroborate; ethanol / 0 - 20 °C / |Inert atmosphere 3: thionyl chloride / dichloromethane / 2 h / |Inert atmosphere; |Reflux View Scheme