3,5-二氟吡啶-2-甲醛合成路线 (共 1 条)
反应条件
1: With diisobutylaluminium hydride in tetrahydrofuran; toluene
T=-20°C; 4 h; Inert atmosphere;
2: With hydrogenchloride; methanol in tetrahydrofuran; water; toluene
pH=4 - 5;
参考文献
Cao, Bin; Wang, Yong; Ding, Kan; Neamati, Nouri; Long, Ya-Qiu
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 6 p. 1239 - 1245