(4R,5S)-2,2,5-三甲基-1,3-二氧戊环-4-羧酸甲酯合成路线 （共 10 条）
反应条件
hydrogen; triethylamine; palladium on activated charcoal in methanol 16 h; Ambient temperature;
参考文献
Mayer, P.; Ahond, A.; Poupat, C.; Potier, P.
Bulletin de la Societe Chimique de France, 1993 , vol. 130, p. 509 - 512
反应条件
lithium aluminium tetrahydride; p-toluenesulfonyl chloride 1.) pyridine; 2.) ether; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 27, # 9 p. 1079 - 1080
反应条件
2: pyridine 3: NaI / butan-2-one / Heating 4: H2/NEt3 / 5percent Pd/C / methanol View Scheme
参考文献
Chemistry Letters, , p. 319 - 322
反应条件
hydrogen; triethylamine; palladium on activated charcoal in methanol
参考文献
Chemistry Letters, , p. 319 - 322
反应条件
toluene-4-sulfonic acid in acetone T=20°C; 4 h;
参考文献
Bianchi, Paola; Roda, Gabriella; Riva, Sergio; Danieli, Bruno; Zabelinskaja-Mackova, Antonina; Griengl, Herfried
Tetrahedron, 2001 , vol. 57, # 11 p. 2213 - 2220
反应条件
1: NaI / butan-2-one / Heating 2: H2/NEt3 / 5percent Pd/C / methanol View Scheme
参考文献
Chemistry Letters, , p. 319 - 322
反应条件
toluene-4-sulfonic acid in acetone 2 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 50, # 26 p. 5865 - 5867
反应条件
1: 58 percent / BH3 / tetrahydrofuran / 8.5 h / 0 °C 2: 1.) TsCl, 2.) LiAlH4 / 1.) pyridine; 2.) ether View Scheme
参考文献
Tetrahedron Letters, , vol. 27, # 9 p. 1079 - 1080
反应条件
1: LiOH / tetrahydrofuran; H2O / 13 h / Ambient temperature 2: diethyl ether View Scheme
参考文献
Helvetica Chimica Acta, , vol. 70, p. 1666 - 1675
反应条件
in diethyl ether Yield given;
参考文献
Helvetica Chimica Acta, , vol. 70, p. 1666 - 1675
