4,5,9,10-四氢苯芘合成路线 （共 65 条）
反应条件
1: Br2 2: o-chloranil / benzene / 24 h / Heating 3: 82 percent / KOH / methanol / 1 h / 20 °C View Scheme
参考文献
Foroozesh, Maryam; Primrose, Ginny; Guo, Zuyu; Bell, L. Chastine; Alworth, William L.; Guengerich, F. Peter
Chemical Research in Toxicology, 1997 , vol. 10, # 1 p. 91 - 102
反应条件
bromine; iron(III) chloride in water
参考文献
Lee, Hongmee; Harvey, Ronald G.
Journal of Organic Chemistry, 1986 , vol. 51, # 14 p. 2847 - 2848
反应条件
hydrogen; Raney nickel W-7 in ethanol 23 h; Ambient temperaturevarious catalysts, various temperature, various solvents, various pressure; Rate constantProduct distribution;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 58, # 7 p. 1962 - 1966
参考文献
Sumalekshmy; Gopidas
New Journal of Chemistry, 2005 , vol. 29, # 2 p. 325 - 331
反应条件
aluminium trichloride in carbon disulfide
2 h; Ambient temperature;
参考文献
Laali, Kenneth K.; Arrica, Maria A.; Okazaki, Takao; Bunge, Scott D.
European Journal of Organic Chemistry, 2008 , # 36 p. 6093 - 6105
反应条件
AlCl3, aluminium chloride in dichloromethane
T=0 - 20°C; Friedel Crafts acylation; 4.5 h;
参考文献
Filichev, Vyacheslav V.; Astakhova, Irina V.; Malakhov, Andrei D.; Korshun, Vladimir A.; Pedersen, Erik B.
Chemistry - A European Journal, 2008 , vol. 14, # 32 p. 9968 - 9980
反应条件
1: 86 percent / 1.) AlCl3, 2.) ice / CS2 / 1.) 0 deg C then RT 2 h
2: 93 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / benzene / 20 h / Heating
3: NaBH4 / methanol / 2 h
4: 79 percent / p-toluenesulfonic acid / benzene / 20 h / Heating
5: 63 percent / m-chloroperbenzoic acid / tetrahydrofuran / 5 h
View Scheme
参考文献
Harvey, Ronald G.; Konieczny, Maria; Pataki, John
Journal of Organic Chemistry, 1983 , vol. 48, # 17 p. 2930 - 2932
反应条件
1: 98 percent / 1.) AlCl3, 2.) ice / CH2Cl2 / 1.) 0 deg C then RT 2 h
2: 98 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / benzene / 72 h / Heating
3: 98 percent / NaBH4 / methanol / 2 h
4: 79 percent / p-toluenesulfonic acid / benzene / 20 h / Heating
5: 73 percent / m-chloroperbenzoic acid / CH2Cl2 / 360 h / 4 °C / phosphate buffer (pH 8)
View Scheme
参考文献
Harvey, Ronald G.; Konieczny, Maria; Pataki, John
Journal of Organic Chemistry, 1983 , vol. 48, # 17 p. 2930 - 2932
反应条件
aluminium trichloride; d-N,a-dimethylphenethylamine in dichloromethane
1.) 0 deg C then RT 2 h;
参考文献
Harvey, Ronald G.; Konieczny, Maria; Pataki, John
Journal of Organic Chemistry, 1983 , vol. 48, # 17 p. 2930 - 2932
反应条件
1: 86 percent / 1.) AlCl3, 2.) ice / CS2 / 1.) 0 deg C then RT 2 h
2: 93 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / benzene / 20 h / Heating
3: NaBH4 / methanol / 2 h
View Scheme
参考文献
Harvey, Ronald G.; Konieczny, Maria; Pataki, John
Journal of Organic Chemistry, 1983 , vol. 48, # 17 p. 2930 - 2932
