4,5,9,10-四氢苯芘合成路线 （共 65 条）
反应条件
1: 86 percent / 1.) AlCl3, 2.) ice / CS2 / 1.) 0 deg C then RT 2 h
2: 93 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / benzene / 20 h / Heating
3: NaBH4 / methanol / 2 h
4: 79 percent / p-toluenesulfonic acid / benzene / 20 h / Heating
View Scheme
参考文献
Harvey, Ronald G.; Konieczny, Maria; Pataki, John
Journal of Organic Chemistry, 1983 , vol. 48, # 17 p. 2930 - 2932
反应条件
1: 98 percent / 1.) AlCl3, 2.) ice / CH2Cl2 / 1.) 0 deg C then RT 2 h
2: 98 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / benzene / 72 h / Heating
3: 98 percent / NaBH4 / methanol / 2 h
View Scheme
参考文献
Harvey, Ronald G.; Konieczny, Maria; Pataki, John
Journal of Organic Chemistry, 1983 , vol. 48, # 17 p. 2930 - 2932
反应条件
1: 1.) Br2, 2.) o-chloranil / 1.) DMF, room temperature, 4 h, 2.) benzene, reflux, 24 h
2: 1.) Mg, ethyl bromide, 2.) B2H6, 3.) 20percent NaOH, 50percent H2O2 / 1.) THF, reflux, 2 h, 2.) reflux, overnight, 3.) reflux, 30 min
View Scheme
参考文献
Harvey, Ronald G.; Schmolka, Sanford; Cortez, Cecilia; Lee, Hongmee
Synthetic Communications, 1988 , vol. 18, # 18 p. 2207 - 2210
反应条件
potassium permanganate; water
参考文献
Coulson
Journal of the Chemical Society, 1937 , p. 1298,1304
反应条件
iodine; sodium hydrogencarbonate in cyclohexane
24 h; Irradiation; Title compound not separated from byproducts;
参考文献
Lai, Yee-Hing; Ang, Slau-Gek; Li, Hwee-Chze; Wong, Siew-Ying
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1992 , # 8 p. 1315 - 1319
