4,4-二甲基-2,3-二氢-1H-萘-1-甲腈合成路线 （共 5 条）
反应条件
PPA; phosphoric acid in toluene
参考文献
Givaudan Corporation
Patent: US4481133 A1, 1984 ;
反应条件
1: water / dimethyl sulfoxide / 2 h / Reflux
2: bismuth trifluoromethanesulphonate / nitromethane / 2 h / Reflux; Inert atmosphere
View Scheme
参考文献
Cacciuttolo, Bastien; Poulain-Martini, Sophie; Dunach, Elisabet
European Journal of Organic Chemistry, 2011 , # 20-21 p. 3710 - 3714
反应条件
1.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
1.2: 2 h / 20 °C / Inert atmosphere
2.1: water / dimethyl sulfoxide / 2 h / Reflux
3.1: bismuth trifluoromethanesulphonate / nitromethane / 2 h / Reflux; Inert atmosphere
View Scheme
参考文献
Cacciuttolo, Bastien; Poulain-Martini, Sophie; Dunach, Elisabet
European Journal of Organic Chemistry, 2011 , # 20-21 p. 3710 - 3714
反应条件
1.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
1.2: 2 h / 20 °C / Inert atmosphere
2.1: water / dimethyl sulfoxide / 2 h / Reflux
3.1: bismuth trifluoromethanesulphonate / nitromethane / 2 h / Reflux; Inert atmosphere
View Scheme
参考文献
Cacciuttolo, Bastien; Poulain-Martini, Sophie; Dunach, Elisabet
European Journal of Organic Chemistry, 2011 , # 20-21 p. 3710 - 3714
参考文献
Givaudan Corporation
Patent: US4481133 A1, 1984 ;
