3-甲氧基-5,6,7,8-四氢萘-2-甲醛合成路线 （共 4 条）
反应条件
trichlorophosphate in N,N-dimethyl-formamide
参考文献
Beight, Douglas Wade; Kinnick, Michael Dean; Lin, Ho-Shen; Morin, John Michael; Richett, Michael Enrico; Sall, Daniel Jon; Sawyer, Jason Scott; Smith, Edward C R
Patent: US2004/77704 A1, 2004 ;
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate
T=0°C; 0.5 h;
2: 6-methoxy-1,2,3,4-tetrahydronaphthalene T=80°C; Vilsmeier reaction; 4 h;
参考文献
Sawyer, J. Scott; Beight, Douglas W.; Smith, Edward C. R.; Snyder, David W.; Chastain, Marcia K.; Tielking, Richard L.; Hartley, Lawrence W.; Carlson, Donald G.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 3 p. 893 - 896
参考文献
Mallory, Frank B.; Rudolph, M. Jonathan; Oh, Soon M.
Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4619 - 4626
反应条件
1: 94 percent / sodium hydroxide / ethanol / 5 h / Heating
2: 60 percent / phosphorus oxychloride
View Scheme
参考文献
Mallory, Frank B.; Rudolph, M. Jonathan; Oh, Soon M.
Journal of Organic Chemistry, 1989 , vol. 54, # 19 p. 4619 - 4626
