1: 1) 2 M butyllithium in n-hexane / 1) ethyl ether, -45 to -35 deg C, 30 min, 2) ethyl ether, room temperature, 24 h 2: MnO2 / diethyl ether / 120 h / Ambient temperature 3: 23 percent / NH2OH*HCl / acetic acid / 6 h / Heating View Scheme

hydrogen; triethylamine; bis(triphenylphosphine)carbonylrhodium(I) chloride in benzene T=105°C; P=68400.1 Torr; 40 h;

1: 1.) Mg / 1) THF, 2 h, room temperature; 2) THF, night 2: H2, Et3N, RhCl(CO)(PPh3)2 / 36 h / 80 - 100 °C / 76000 Torr View Scheme

1: SOCl2, pyridine 2: 1.) Mg / 1) THF, 2 h, room temperature; 2) THF, night 3: H2, Et3N, RhCl(CO)(PPh3)2 / 36 h / 80 - 100 °C / 76000 Torr View Scheme

1: 1.) Mg / 1) THF, 2 h, room temperature; 2) THF, night 2: H2, Et3N, RhCl(CO)(PPh3)2 / 36 h / 80 - 100 °C / 76000 Torr View Scheme