N,N-二甲基咪唑-1-磺酰胺合成路线 （共 24 条）
反应条件
triethylamine in toluene T=20°C; 8 h;
参考文献
Dainippon Sumitomo Pharma Co., Ltd.
Patent: EP1647546 A1, 2006 ;
Location in patent: Page/Page column 30 ;
参考文献
Casara, Patrick; Diguarher, Thierry Le; Dorey, Gilbert; Hickman, John; Pierre, Alain; Tucker, Gordon; Guilbaud, Nicolas
Patent: US2002/156113 A1, 2002 ;
反应条件
in acetonitrile T=20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 14 p. 4896 - 4899
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran 0.5 h; Ambient temperatureother reagents, time; Product distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 6 p. 1645 - 1648
反应条件
methanesulfonic acid; phosphorous pentoxide T=70 - 90°C; 12 h;
参考文献
Kaboudin, Babak; Haghighat, Hamideh
Journal of the Iranian Chemical Society, 2012 , vol. 9, # 6 p. 951 - 955
反应条件
methanesulfonic acid; phosphorous pentoxide T=70 - 90°C; 8 h; SolventTemperatureTime;
参考文献
Kaboudin, Babak; Haghighat, Hamideh
Journal of the Iranian Chemical Society, 2012 , vol. 9, # 6 p. 951 - 955
反应条件
methanesulfonic acid; phosphorous pentoxide T=70 - 90°C; 8 h;
参考文献
Kaboudin, Babak; Haghighat, Hamideh
Journal of the Iranian Chemical Society, 2012 , vol. 9, # 6 p. 951 - 955
反应条件
1: in tetrahydrofuran T=-78°C; 0.333333 h; 2: With tert-butyldimethylsilyl chloride in tetrahydrofuran T=-78 - 20°C; 3: With N-fluoro-N-(phenylsulfonyl)benzene-sulfonamide in tetrahydrofuran T=-78°C; 1 h;
参考文献
GLAXO GROUP LIMITED; DI FABIO, Romano; GIANOTTI, Massimo; LESLIE, Colin Philip; STASI, Luigi Piero
Patent: WO2010/142652 A1, 2010 ;
Location in patent: Page/Page column 44-45 ;
WO 2010/142652 A1
反应条件
1: N,N-Dimethyl-1H-imidazole-1-sulphonamide With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2: tert-butyldimethylsilyl chloride in tetrahydrofuran; hexane T=-78 - 20°C;
参考文献
Gianotti, Massimo; Corti, Corrado; Fratte, Sonia Delle; Di Fabio, Romano; Leslie, Colin P.; Pavone, Francesca; Piccoli, Laura; Stasi, Luigi; Wigglesworth, Mark J.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 17 p. 5069 - 5073
反应条件
1: N,N-Dimethyl-1H-imidazole-1-sulphonamide With n-butyllithium in tetrahydrofuran T=-78°C; 1 h; 2: tert-butyldimethylsilyl chloride in tetrahydrofuran T=20°C; 24 h;
参考文献
WO2003/99795 A1, ;
Page 78, 79 ;
WO 03/099795 A1
