4-(1H-四氮唑-1-基)苯甲酸合成路线 (共 4 条)
反应条件
1: With water; sodium hydroxide in methanol T=20°C; 2 h; 2: With hydrogenchloride in methanol; water
参考文献
WO2012/123449 A1, ;
Page/Page column 87 ;
WO 2012/123449 A1
反应条件
acetic acid T=100°C; 0.166667 h;
参考文献
Karimi Zarchi, Mohammad Ali; Nazem, Fatemeh
Journal of the Iranian Chemical Society, 2014 , vol. 11, # 1 p. 91 - 99
反应条件
1: sodium azide; acetic acid / 4 h / Reflux 2: sodium hydroxide; water / methanol / 2 h / 20 °C View Scheme
参考文献
WO2012/123449 A1, ;
WO 2012/123449 A1
反应条件
potassium hydroxide; dimethyl sulfoxide in ethanol
参考文献
Voitekhovich; Vorob'ev; Gaponik; Ivashkevich
Chemistry of Heterocyclic Compounds, 2005 , vol. 41, # 8 p. 999 - 1004