1: 2,6-lutidine; DMAP / CH2Cl2 / -78 - 20 °C
2: triethylamine / PdCl2(PPh3)2 / dimethylformamide / 3 h / 80 °C
3: H2 / Pd-C / ethanol / 1 h
4: 0.22 g / CrO3; H2SO4 / acetone; H2O / 1.33 h
View Scheme
参考文献
Murphy, Paul V.; Hubbard, Rod E.; Manallack, David T.; Wills, Ruth E.; Montana, John G.; Taylor, Richard J. K.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2421 - 2439
Murphy, Paul V.; Hubbard, Rod E.; Manallack, David T.; Wills, Ruth E.; Montana, John G.; Taylor, Richard J. K.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2421 - 2439
1: triethylamine / PdCl2(PPh3)2 / dimethylformamide / 3 h / 80 °C
2: H2 / Pd-C / ethanol / 1 h
3: 0.22 g / CrO3; H2SO4 / acetone; H2O / 1.33 h
View Scheme
参考文献
Murphy, Paul V.; Hubbard, Rod E.; Manallack, David T.; Wills, Ruth E.; Montana, John G.; Taylor, Richard J. K.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2421 - 2439
Murphy, Paul V.; Hubbard, Rod E.; Manallack, David T.; Wills, Ruth E.; Montana, John G.; Taylor, Richard J. K.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2421 - 2439
Murphy, Paul V.; Hubbard, Rod E.; Manallack, David T.; Wills, Ruth E.; Montana, John G.; Taylor, Richard J. K.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2421 - 2439
Murphy, Paul V.; Hubbard, Rod E.; Manallack, David T.; Wills, Ruth E.; Montana, John G.; Taylor, Richard J. K.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2421 - 2439
Murphy, Paul V.; Hubbard, Rod E.; Manallack, David T.; Wills, Ruth E.; Montana, John G.; Taylor, Richard J. K.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2421 - 2439
Murphy, Paul V.; Hubbard, Rod E.; Manallack, David T.; Wills, Ruth E.; Montana, John G.; Taylor, Richard J. K.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2421 - 2439
Murphy, Paul V.; Hubbard, Rod E.; Manallack, David T.; Wills, Ruth E.; Montana, John G.; Taylor, Richard J. K.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 12 p. 2421 - 2439
