2,4-二氯-N-异丙基苯胺合成路线 (共 3 条)
反应条件
1: With sodium tris(acetoxy)borohydride in 1,2-dichloro-ethane
T=20°C; 18 h;
2: With water; sodium hydrogencarbonate in 1,2-dichloro-ethane
参考文献
Amgen Inc.
Patent: US2006/293392 A1, 2006 ;
Location in patent: Page/Page column 47-48 ;
反应条件
sodium tris(acetoxy)borohydride; acetic acid in 1,2-dichloro-ethane
T=20°C; 2 h;
参考文献
Reddy, T. Jagadeeswar; Leclair, Michael; Proulx, Melanie
Synlett, 2005 , # 4 art. no. S07004ST, p. 583 - 586
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/821 A1, 2005 ;
Location in patent: Page 59 ;
WO 2005/000821 A1