t-丁基(2S)-2-[(苄基氧基羰基氨基)]-4-羟基丁酸酯合成路线 (共 2 条)
反应条件
trifluoroacetic acid in dichloromethane 0.5 h; Ambient temperature;
参考文献
Easmon; Heinisch; Holzer; Matuszczak
Archiv der Pharmazie, 1995 , vol. 328, # 4 p. 367 - 370
反应条件
1: 84 percent / KMnO4 / acetone; acetic acid / 3.5 h / Ambient temperature 2: 1.) N-methylmorpholine, isobutyl chloroformate; 2.) NH3 / 1.) THF, 7 min, -20 deg C; 2.) water, 2 h, -15 -> 10 deg C View Scheme
参考文献
Vasella, Andrea; Voeffray, Robert
Journal of the Chemical Society, Chemical Communications, 1981 , # 3 p. 97 - 98