(2,6-二硝基苯基)乙醛合成路线 （共 3 条）
反应条件
in N,N-dimethyl-formamide
T=125°C; 24 h;
参考文献
Kozikowski, Alan P.; Greco, Michael N.; Springer, James P.
Journal of the American Chemical Society, 1982 , vol. 104, # 26 p. 7622 - 7626
反应条件
in N,N-dimethyl-formamide
9 h; Heating;
参考文献
Somei; Inoue; Tokutake; et al.
Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 3 p. 726 - 738
反应条件
1: 93 percent / Nh4Cl / ethanol / 24 h / Heating
2: 63 percent / LiOH / hexamethylphosphoric acid triamide / 24 h / Ambient temperature
3: 1.) H2, 2.) 6N HCl / 1.) 5percent Pd/C sulfided catalyst / 1.) EtOAc, 40 psi, 3 h, 2.) CH2Cl2, reflux, 2 h
4: 92 percent / SnCl4 / benzene / 1.) 0 deg C, 20 min, 2.) room temperature, 2 h
View Scheme
参考文献
Kozikowski, Alan P.; Greco, Michael N.; Springer, James P.
Journal of the American Chemical Society, 1982 , vol. 104, # 26 p. 7622 - 7626
