D-3-(1-萘基)-丙氨酸盐酸盐合成路线 （共 7 条）
反应条件
hydrogen; palladium dihydroxide in tetrahydrofuran; methanol P=3102.9 Torr; 19 h;
参考文献
Lander, Peter A.; Hegedus, Louis S.
Journal of the American Chemical Society, 1994 , vol. 116, # 18 p. 8126 - 8132
反应条件
chiral stationary phase including isopropyl-functionalized CF6 in methanol; acetic acid; triethylamine; acetonitrile T=0°C; Purification / work up;
参考文献
WO2010/148191 A2, ;
Page/Page column 45-49; 61 ;
反应条件
hydrogenchloride 2 h; Heating;
参考文献
Rodriguez; Bernad; Galas; Lignon; Laur; Aumelas; Martinez
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 3 p. 245 - 253
反应条件
1: 87 percent / 1 M NaOH / aq. ethanol / 6 h / Ambient temperature 2: 94 percent / 0.17 h / 160 °C 3: 96 percent 4: 55 percent / 6 N aq. HCl / 2 h / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 26, # 3 p. 245 - 253
反应条件
1: 90 percent / EtONa / ethanol / 6 h / Heating 2: 87 percent / 1 M NaOH / aq. ethanol / 6 h / Ambient temperature 3: 94 percent / 0.17 h / 160 °C 4: 96 percent 5: 55 percent / 6 N aq. HCl / 2 h / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 26, # 3 p. 245 - 253
反应条件
1: 94 percent / 0.17 h / 160 °C 2: 96 percent 3: 55 percent / 6 N aq. HCl / 2 h / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 26, # 3 p. 245 - 253
反应条件
1: 96 percent 2: 55 percent / 6 N aq. HCl / 2 h / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 26, # 3 p. 245 - 253
