1-(2-氟-3,6-二甲氧基苯基)乙醇合成路线 (共 1 条)
反应条件
1: 1,4-dimethoxy-2-fluorobenzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.5 h;
2: acetaldehyde in tetrahydrofuran; hexane
0.5 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/65508 A1, 2008 ;
Location in patent: Page/Page column 25 ;