6-氟-2(3h)-苯并噻唑酮肼酮合成路线 （共 7 条）
参考文献
Vaid, R. K.; Dhindsa, G. S.; Kaushik, B.; Singh, S. P.; Dhawan, S. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 569 - 570
反应条件
T=160°C; Yield given;
参考文献
Vaid, Radhe K.; Dhindsa, Gurnam S.; Kaushik, Beena; Singh, Shiv P.
Organic Mass Spectrometry, 1987 , vol. 22, p. 36 - 38
反应条件
thionyl chloride T=50°C; 2 h;
参考文献
Byeon, Seong Rim; Jin, Yun Jung; Lim, Soo Jeong; Lee, Ji Hoon; Yoo, Kyung Ho; Shin, Kye Jung; Oh, Seung Jun; Kim, Dong Jin
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 14 p. 4022 - 4025
反应条件
hydrogenchloride; hydrazine hydrate in ethylene glycol
Microwave irradiation;
参考文献
Munirajasekhar; Himaja; Mali, Sunil V.
Journal of Heterocyclic Chemistry, 2014 , vol. 51, # 2 p. 459 - 465
反应条件
1: 32 percent / Br2; AcOH / 1 h / cooling
2: 85 percent / NH2NH2*H2O; NH2NH2*H2SO4 / ethane-1,2-diol / 2 h / 120 °C
View Scheme
参考文献
Byeon, Seong Rim; Jin, Yun Jung; Lim, Soo Jeong; Lee, Ji Hoon; Yoo, Kyung Ho; Shin, Kye Jung; Oh, Seung Jun; Kim, Dong Jin
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 14 p. 4022 - 4025
反应条件
hydrazine hydrate in ethanol; water
3 h; Reflux;
参考文献
Stella, Alessandro; Segers, Kenneth; De Jonghe, Steven; Vanderhoydonck, Bart; Rozenski, Jef; Anne, Jozef; Herdewijn, Piet
Chemistry and Biodiversity, 2011 , vol. 8, # 2 p. 253 - 265
反应条件
hydrogenchloride in ethanol
Heating;
参考文献
Singh, S. P.; Kodali, Dharma R.; Prakash, Indra; Prakash, Om; Sawhney, S. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 2 p. 125 - 128
