1.1: sodium hydroxide / water; acetone / 3 h / 0 °C / Inert atmosphere 1.2: 0.5 h / 0 °C / Inert atmosphere 2.1: potassium carbonate / N,N-dimethyl-formamide / 32 h / 20 °C / Inert atmosphere 3.1: sodium methylate / methanol / 9.5 h / 20 °C / Inert atmosphere 4.1: palladium 10 on activated carbon; hydrogen / ethanol; ethyl acetate / 20 °C / Inert atmosphere View Scheme