2,3,4,5,6-五氟联苯合成路线 （共 79 条）
反应条件
Cu2Cl2; sulfuric acid; copper(II) sulfate; sodium nitrite; benzene; B(3,5-bis(trifluoromethyl)phenyl)4- 1) 0 deg C, dichloromethane, water, 2) dichloromethane, water , 100 min, rt.; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Fluorine Chemistry, , vol. 24, p. 535 - 537
参考文献
Chen, Qing-Yun; Li, Zhan-Ting
Journal of Organic Chemistry, 1993 , vol. 58, # 9 p. 2599 - 2604
反应条件
1: silver(l) oxide; potassium carbonate; 2,2,2-trimethylacetic acid / N,N-dimethyl-formamide / 16 h / 50 °C / |Inert atmosphere 2: (hydroxy(tosyloxy)iodo)benzene / 1,2-dichloro-ethane / 16 h / 50 °C / |Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 6 p. 1781 - 1784
Angew. Chem., , vol. 125, # 6 p. 1825 - 1828,4
反应条件
1: tetrahydrofuran / 5 h / 60 °C / |Inert atmosphere; |Glovebox 2: lithium iodide / THF-d8 (tetrahydrofuran-d8) / 7 h / 60 °C / |Inert atmosphere; |Glovebox View Scheme
参考文献
Chemistry - A European Journal, , vol. 20, # 7 p. 2040 - 2048
反应条件
Cu2Cl2; sulfuric acid; copper(II) sulfate; sodium nitrite; B(3,5-bis(trifluoromethyl)phenyl)4- 1) 0 deg C, dichloromethane, water, 5 min 2) dichloromethane, water 100 min, rt.; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Fluorine Chemistry, , vol. 24, p. 535 - 537
反应条件
pyridine in diethyl ether
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 763 - 769
反应条件
potassium iodide in acetonitrile 0.166667 h;
参考文献
Kosynkin, Dmitry; Bockman, T. Michael; Kochi, Jay K.
Journal of the Chemical Society. Perkin Transactions 2, 1997 , # 10 p. 2003 - 2012
反应条件
NiCl2((PPh3)P)2 in tetrahydrofuran addn. of Ni-catalyst and alkyl halide to soln. of PhYbI (prepd. in situ from Yb metal and PhI in THF), agitation (25°C); GLC;
参考文献
Rybakova, L. F.; Syutkina, O. P.; Garbar, A. V.; Petrov, E. S.
Journal of General Chemistry USSR (English Translation), 1988 , vol. 58, p. 934 - 936
Zhurnal Obshchei Khimii, 1988 , vol. 58, p. 1053 - 1055
反应条件
n-butyllithium 1.) THF, Et2O, hexane, -110 deg C, 30 min, 2.) THF, Et2O, hexane, -110 deg C, 2 h; Multistep reaction. Title compound not separated from byproducts;
参考文献
Journal of Organometallic Chemistry, , vol. 193, # 3 p. 283 - 292
反应条件
ytterbium 1.) THF, 2.) THF, 30 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 33, # 10 p. 2181 - 2183
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 10 p. 2386 - 2388
