2-苯基巯基苯并吡喃-4-酮合成路线 （共 59 条）
反应条件
PPA
T=90 - 100°C; 1 h;
参考文献
Nakazumi, Hiroyuki; Kitaguchi, Tooru; Ueyama, Tamio; Kitao, Teijiro
Synthesis, 1984 , # 6 p. 518 - 520
反应条件
1: oxalyl chloride
2: 85 percent / aluminum chloride / CH2Cl2 / 1 h / Ambient temperature
View Scheme
参考文献
Detty,M.R.; Murray,B.J.
Journal of the American Chemical Society, 1983 , vol. 105, p. 883
反应条件
1: NaOEt / ethanol
2: 86 percent / aq. potassium hydroxide / ethanol / 2 h / 50 °C
3: oxalyl chloride
4: 85 percent / aluminum chloride / CH2Cl2 / 1 h / Ambient temperature
View Scheme
参考文献
Detty,M.R.; Murray,B.J.
Journal of the American Chemical Society, 1983 , vol. 105, p. 883
反应条件
1: NaOEt / ethanol
2: 86 percent / aq. potassium hydroxide / ethanol / 2 h / 50 °C
3: oxalyl chloride
4: 85 percent / aluminum chloride / CH2Cl2 / 1 h / Ambient temperature
View Scheme
参考文献
Detty,M.R.; Murray,B.J.
Journal of the American Chemical Society, 1983 , vol. 105, p. 883
反应条件
P2O5; methanesulfonic acid
参考文献
Wadsworth, Donald H.; Detty, Michael R.
Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4611 - 4615
反应条件
iodine; sodium hydrogencarbonate in 1-methyl-pyrrolidin-2-one
4 h; Reflux;
参考文献
Kobayashi, Kazuhiro; Kobayashi, Akihiro; Ezaki, Kosuke
Heterocycles, 2012 , vol. 85, # 8 p. 1997 - 2004
参考文献
Holshouser, Mark H.; Loeffler, Larry J.; Hall, Iris H.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 7 p. 853 - 858
反应条件
Na2S*9H2O in ethanol
T=90°C; Michael addition; 1.5 h; Microwave cavity;
参考文献
Willy, Benjamin; Mueller, Thomas J. J.
Synlett, 2009 , # 8 p. 1255 - 1260
反应条件
in tetrahydrofuran
Wittig cyclization; 18 h; Heating;
参考文献
Kumar, Pradeep; Bodas, Mandar S
Tetrahedron, 2001 , vol. 57, # 48 p. 9755 - 9758
反应条件
in toluene
8 h; Heating;
参考文献
Kumar, Pradeep; Rao, Ashok T.; Pandey, Bipin
Journal of the Chemical Society, Chemical Communications, 1992 , # 21 p. 1580 - 1581
