hydrogenchloride in acetic acid 4 h; Heating;

<b>Multi-step reaction with 6 steps<br /> </b>1: 1.) sodium hydride / 1.0 DMF, 2.) DMF, 16 h<br />2: 90 percent / aq. methanolic sodium hydroxide / 3 h / Heating<br />3: thionyl chloride<br />4: aluminum chloride / CH₂Cl₂ / 0.5 h / 0 &deg;C<br />5: CH₂Cl₂; diethyl ether / 0.5 h<br />6: silver benzoate / 0.08 h / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: thionyl chloride<br />2: aluminum chloride / CH₂Cl₂ / 0.5 h / 0 &deg;C<br />3: CH₂Cl₂; diethyl ether / 0.5 h<br />4: silver benzoate / 0.08 h / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 6 steps<br /> </b>1: 1.) sodium hydride / 1.0 DMF, 2.) DMF, 16 h<br />2: 90 percent / aq. methanolic sodium hydroxide / 3 h / Heating<br />3: thionyl chloride<br />4: aluminum chloride / CH₂Cl₂ / 0.5 h / 0 &deg;C<br />5: CH₂Cl₂; diethyl ether / 0.5 h<br />6: silver benzoate / 0.08 h / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 7 steps<br /> </b>1: 60 percent / pyridine / 24 h / Ambient temperature<br />2: 1.) sodium hydride / 1.0 DMF, 2.) DMF, 16 h<br />3: 90 percent / aq. methanolic sodium hydroxide / 3 h / Heating<br />4: thionyl chloride<br />5: aluminum chloride / CH₂Cl₂ / 0.5 h / 0 &deg;C<br />6: CH₂Cl₂; diethyl ether / 0.5 h<br />7: silver benzoate / 0.08 h / Heating<br /> <br /> &nbsp;