2-羟基-5-辛酰-N-[3-(三氟甲基)苯基]苯甲酰胺合成路线 （共 6 条）
反应条件
hydrogenchloride in methanol; water
参考文献
Lever Brothers Company
Patent: US4701527 A1, 1987 ;
反应条件
1: PCl3 / chlorobenzene / 0.25 h / Heating
2: chlorobenzene / 3 h / Heating
View Scheme
参考文献
Coburn; Batista; Evans; Genco
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1245 - 1249
反应条件
1: 93 percent / aq. NaOH / ethanol / 6 h / Heating
2: PCl3 / chlorobenzene / 0.25 h / Heating
3: chlorobenzene / 3 h / Heating
View Scheme
参考文献
Coburn; Batista; Evans; Genco
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1245 - 1249
反应条件
1: 85 percent / aluminum chloride / CS2 / 12 h
2: 93 percent / aq. NaOH / ethanol / 6 h / Heating
3: PCl3 / chlorobenzene / 0.25 h / Heating
4: chlorobenzene / 3 h / Heating
View Scheme
参考文献
Coburn; Batista; Evans; Genco
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1245 - 1249
反应条件
1: 85 percent / aluminum chloride / CS2 / 12 h
2: 93 percent / aq. NaOH / ethanol / 6 h / Heating
3: PCl3 / chlorobenzene / 0.25 h / Heating
4: chlorobenzene / 3 h / Heating
View Scheme
参考文献
Coburn; Batista; Evans; Genco
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1245 - 1249
反应条件
in chlorobenzene
3 h; Heating;
参考文献
Coburn; Batista; Evans; Genco
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1245 - 1249
