7-表-10-脱乙酰基紫杉醇合成路线 (共 14 条)
反应条件
sodium hydrogencarbonate in tetrahydrofuran
参考文献
Hauser, Inc.
Patent: US5629433 A1, 1997 ;
反应条件
acetic acid; zinc in methanol T=60°C; 2 h;
参考文献
Mangatal; Adeline; Guenard; Gueritte-Voegelein; Potier
Tetrahedron, 1989 , vol. 45, # 13 p. 4177 - 4190
反应条件
dihydrogen peroxide; sodium hydrogencarbonate in tetrahydrofuran 24 h; Ambient temperature;
参考文献
Zheng, Qun Y.; Darbie, Lynn G.; Cheng, Xiaoqin; Murray, Christopher K.
Tetrahedron Letters, 1995 , vol. 36, # 12 p. 2001 - 2004
反应条件
zinc dibromide in methanol 48 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 49, # 14 p. 2805 - 2828
反应条件
Glycine max; BG-11 medium T=25°C;
参考文献
Chemistry Letters, , vol. 37, # 3 p. 362 - 363
反应条件
1: pyridine / 3 h / Ambient temperature 2: 90 percent / Zn, AcOH / methanol / 2 h / 60 °C View Scheme
参考文献
Tetrahedron, , vol. 45, # 13 p. 4177 - 4190
反应条件
1: pyridine / 3 h / Ambient temperature 2: 90 percent / Zn, AcOH / methanol / 2 h / 60 °C View Scheme
参考文献
Tetrahedron, , vol. 45, # 13 p. 4177 - 4190
反应条件
1: 75 percent / ISi(CH3)3 / acetonitrile / 0.5 h / 0 °C 2: pyridine / 3 h / Ambient temperature 3: 90 percent / Zn, AcOH / methanol / 2 h / 60 °C View Scheme
参考文献
Tetrahedron, , vol. 45, # 13 p. 4177 - 4190
反应条件
Marchantia polymorpha; BG-11 medium T=25°C; Further byproducts.;
参考文献
Chemistry Letters, , vol. 37, # 3 p. 362 - 363
反应条件
α-tocopherylpolyethyleneglycol-100 succinate; poloxamer 407; 2,5,7,8-tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol in water T=4°C; 7305 h; Product distribution; Further Variations:Temperaturestime of storage;
参考文献
Pharmaceutical Research, , vol. 17, # 2 p. 175 - 182