7-表-10-脱乙酰基紫杉醇合成路线 （共 14 条）
参考文献
NaPro BioTherapeutics, Inc.
Patent: US5256801 A1, 1993 ;
反应条件
1: 10-deacetyl taxol(7α-OH) With 2-chloro-acetamide in tetrahydrofuran T=100°C; 3 h; 2: acetic anhydride in tetrahydrofuran T=100°C; 3 h; 3: With methanol; sodium hydrogencarbonate; thiourea T=20°C; 1 h; Product distribution / selectivity;
参考文献
Tano, Dingning; Li, Jian
Patent: US2008/287696 A1, 2008 ;
Location in patent: Page/Page column 6; 7 ;
反应条件
acetic anhydride; sodium hydrogencarbonate; thiourea in pyridine; ethanol; chloroform; acetone
参考文献
University of Florida
Patent: US5367086 A1, 1994 ;
反应条件
1: 10-deacetyl taxol(7α-OH) With cerium(III) chloride in tetrahydrofuran
T=20°C; 0.5 h;
2: acetic anhydride in tetrahydrofuran
T=20°C; 2 h; Product distribution / selectivity;
参考文献
Tano, Dingning; Li, Jian
Patent: US2008/287696 A1, 2008 ;
Location in patent: Page/Page column 4-5 ;
