5,6,7,8-四氢-gamma-氧萘-2-丁酸合成路线 （共 32 条）
反应条件
AlCl3, aluminium chloride in tetrachloroethane, 1,1,2,2-
T=20°C; Friedel-Crafts acylation; Cooling with ice;
参考文献
Zhang, Zhenfa; Sangaiah, Ramiah; Gold, Avram; Ball, Louise M.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 15 p. 5431 - 5435
反应条件
1.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C
1.2: 120 - 215 °C
2.1: AlCl3, aluminium chloride / tetrachloroethane, 1,1,2,2- / 20 °C / Cooling with ice
View Scheme
参考文献
Zhang, Zhenfa; Sangaiah, Ramiah; Gold, Avram; Ball, Louise M.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 15 p. 5431 - 5435
反应条件
1.1: methanesulfonic acid / 0.5 h / 90 °C / Inert atmosphere
2.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C
2.2: 120 - 215 °C
3.1: AlCl3, aluminium chloride / tetrachloroethane, 1,1,2,2- / 20 °C / Cooling with ice
View Scheme
参考文献
Zhang, Zhenfa; Sangaiah, Ramiah; Gold, Avram; Ball, Louise M.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 15 p. 5431 - 5435
反应条件
1.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C
1.2: 120 - 215 °C
2.1: methanesulfonic acid / 0.5 h / 90 °C / Inert atmosphere
3.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C
3.2: 120 - 215 °C
4.1: AlCl3, aluminium chloride / tetrachloroethane, 1,1,2,2- / 20 °C / Cooling with ice
View Scheme
参考文献
Zhang, Zhenfa; Sangaiah, Ramiah; Gold, Avram; Ball, Louise M.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 15 p. 5431 - 5435
反应条件
1.1: AlCl3, aluminium chloride / tetrachloroethane, 1,1,2,2-
2.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C
2.2: 120 - 215 °C
3.1: methanesulfonic acid / 0.5 h / 90 °C / Inert atmosphere
4.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C
4.2: 120 - 215 °C
5.1: AlCl3, aluminium chloride / tetrachloroethane, 1,1,2,2- / 20 °C / Cooling with ice
View Scheme
参考文献
Zhang, Zhenfa; Sangaiah, Ramiah; Gold, Avram; Ball, Louise M.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 15 p. 5431 - 5435
反应条件
1: phosphorus pentoxide / 190 °C
3: 130 - 140 °C
View Scheme
参考文献
Schroeter
Chemische Berichte, 1924 , vol. 57, p. 2014
Chem. Zentralbl., 1928 , vol. 99, # II p. 1386
反应条件
2: 130 - 140 °C
View Scheme
参考文献
Schroeter
Chemische Berichte, 1924 , vol. 57, p. 2014
Chem. Zentralbl., 1928 , vol. 99, # II p. 1386
参考文献
Schroeter
Chemische Berichte, 1924 , vol. 57, p. 2014
Chem. Zentralbl., 1928 , vol. 99, # II p. 1386
参考文献
Martin; Stoffyn
Bulletin des Societes Chimiques Belges, 1950 , vol. 59, p. 83,87
参考文献
Krollpfeiffer; Schaefer
Chemische Berichte, 1923 , vol. 56, p. 630
