N-甲基-beta-咔啉-3-羧酰胺合成路线 （共 9 条）
参考文献
A/S Ferrosan; Scherling AG
Patent: US4371536 A1, 1983 ;
US 4371536 A
反应条件
1: H2SO4 / H2O / 2 h / Ambient temperature
2: HCl gas / Heating
3: 70 percent / 18 h / Ambient temperature
4: 80 percent / MnO2 / methylamine / 18 h / Ambient temperature
View Scheme
参考文献
Couts, Ronald T.; Micetich, Ronald G.; Baker, Glen B; Benderly, Abraham; Dewhurst, Tim; et al.
Heterocycles, 1984 , vol. 22, # 1 p. 131 - 142
反应条件
1: HCl gas / Heating
2: 70 percent / 18 h / Ambient temperature
3: 80 percent / MnO2 / methylamine / 18 h / Ambient temperature
View Scheme
参考文献
Couts, Ronald T.; Micetich, Ronald G.; Baker, Glen B; Benderly, Abraham; Dewhurst, Tim; et al.
Heterocycles, 1984 , vol. 22, # 1 p. 131 - 142
反应条件
1: 70 percent / 18 h / Ambient temperature
2: 80 percent / MnO2 / methylamine / 18 h / Ambient temperature
View Scheme
参考文献
Couts, Ronald T.; Micetich, Ronald G.; Baker, Glen B; Benderly, Abraham; Dewhurst, Tim; et al.
Heterocycles, 1984 , vol. 22, # 1 p. 131 - 142
反应条件
T=60°C; Substitution; pH=7.4; 120 h;
参考文献
Manabe, Shigeo; Juan, Yuan; Wada, Osamu; Ueki, Akira; Kanai, Yoshikatsu
Environmental Pollution (Amsterdam, Netherlands), 1995 , vol. 89, # 3 p. 329 - 336
反应条件
T=60°C; Substitution; pH=7.4; 120 h;
参考文献
Manabe, Shigeo; Juan, Yuan; Wada, Osamu; Ueki, Akira; Kanai, Yoshikatsu
Environmental Pollution (Amsterdam, Netherlands), 1995 , vol. 89, # 3 p. 329 - 336
反应条件
T=200°C; Decomposition; substitution; 1.5 h;
参考文献
Manabe, Shigeo; Juan, Yuan; Wada, Osamu; Ueki, Akira; Kanai, Yoshikatsu
Environmental Pollution (Amsterdam, Netherlands), 1995 , vol. 89, # 3 p. 329 - 336
参考文献
Lin, Guowu; Wang, Yue; Zhou, Qingfa; Tang, Weifang; Wang, Jian; Lu, Tao
Molecules, 2010 , vol. 15, # 8 p. 5680 - 5691
反应条件
sodium methylate
1.) dimethylformamid, room temp., 2 h, 2.) dimethylformamid, reflux, 2 h; Multistep reaction;
参考文献
Frehel, Daniel; Maffrand, Jean-Pierre
Heterocycles, 1984 , vol. 22, # 1 p. 143 - 149
