(4-甲基苯基)(2-吡啶基)甲酮合成路线 （共 25 条）
反应条件
potassium tert-butylate in dichloromethane T=10°C; 3 h;
参考文献
Reddy, R. Chandrasekara; Venkateswara Rao; Narayana Swamy; Hareesh Kumar
Organic Preparations and Procedures International, 2009 , vol. 41, # 2 p. 168 - 171
反应条件
1: With potassium tert-butylate in dichloromethane T=10 - 20°C; Wittig reaction; 2: With methanesulfonic acid T=190°C; 6 h; Further stages;
参考文献
Reddy, R. Chandrasekara; Venkateswara Rao; Narayana Swamy; Hareesh Kumar
Organic Preparations and Procedures International, 2009 , vol. 41, # 2 p. 168 - 171
反应条件
potassium tert-butylate in dichloromethane T=10°C; 3 h;
参考文献
Reddy, R. Chandrasekara; Venkateswara Rao; Narayana Swamy; Hareesh Kumar
Organic Preparations and Procedures International, 2009 , vol. 41, # 2 p. 168 - 171
反应条件
1: With potassium tert-butylate in dichloromethane T=10 - 20°C; Wittig reaction; 2: With methanesulfonic acid T=190°C; 6 h; Further stages;
参考文献
Reddy, R. Chandrasekara; Venkateswara Rao; Narayana Swamy; Hareesh Kumar
Organic Preparations and Procedures International, 2009 , vol. 41, # 2 p. 168 - 171
反应条件
1: alpha-chloropyridine With magnesium in tetrahydrofuran
T=40°C; 2 h;
2: 4-MeC6H4CONMe2 in tetrahydrofuran
T=40°C; 5 h;
3: With water; ammonium chloride in tetrahydrofuran
T=10°C;
参考文献
VITTAL MALLYA SCIENTIFIC RESEARCH FOUNDATION
Patent: WO2007/141803 A2, 2007 ;
Location in patent: Page/Page column 6 ;
反应条件
1: in diethyl ether
T=0°C; 40 h; Heating / reflux;
2: With sulfuric acid in water
0.333333 h;
参考文献
AnorMED, Inc.
Patent: US6750348 B1, 2004 ;
Location in patent: Page column 114-115 ;
US 6750348 B1
反应条件
manganese(IV) oxide in dichloromethane
11 h;
参考文献
Hirayama, Tasuku; Ueda, Satoshi; Okada, Takahiro; Tsurue, Norihiko; Okuda, Kensuke; Nagasawa, Hideko
Chemistry - A European Journal, 2014 , vol. 20, # 14 p. 4156 - 4162
反应条件
in tetrahydrofuran; magnesium
参考文献
J. URIACH and CIA. S.A.
Patent: EP669333 A1, 1995 ;
反应条件
potassium carbonate in tetrahydrofuran
3 h; Heating;
参考文献
De Kimpe, Norbert; Keppens, Marian; Fonck, Gwendolien
Chemical Communications, 1996 , # 5 p. 635 - 636
反应条件
copper(l) iodide; oxygen; acetic acid in dimethyl sulfoxide
T=100°C; 24 h;
参考文献
Pieber, Bartholomaeus; Kappe, C. Oliver
Green Chemistry, 2013 , vol. 15, # 2 p. 320 - 324
