(9ci)-1-甲基-1H-苯并咪唑-2-羧酸肼合成路线 （共 5 条）
反应条件
1: With hydrogenchloride; sodium nitrite in water T=20°C; 1 h; 2: With hydrogenchloride T=80°C; 1 h;
参考文献
Ohta, Shunsaku; Tsuno, Naoki; Nakamura, Seikou; Taguchi, Norio; Yamashita, Masayuki; Kawasaki, Ikuo; Fujieda, Mieko
Heterocycles, 2000 , vol. 53, # 9 p. 1939 - 1955
反应条件
hydrazine hydrate in isopropyl alcohol
T=60°C; 1 h;
参考文献
Musser, John H.; Brown, Richard E.; Loev, Bernard; Bailey, Kevin; Jones, Howard; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 121 - 125
反应条件
hydrazine hydrate in ethanol
Heating;
参考文献
Ohta, Shunsaku; Tsuno, Naoki; Nakamura, Seikou; Taguchi, Norio; Yamashita, Masayuki; Kawasaki, Ikuo; Fujieda, Mieko
Heterocycles, 2000 , vol. 53, # 9 p. 1939 - 1955
反应条件
1: 62 percent / 48 h / Heating
2: 91 percent / 85percent aq. hydrazine / propan-2-ol / 1 h / 60 °C
View Scheme
参考文献
Musser, John H.; Brown, Richard E.; Loev, Bernard; Bailey, Kevin; Jones, Howard; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 121 - 125
反应条件
1.1: n-BuLi / hexane; tetrahydrofuran / 0.5 h / -78 °C
1.2: 27 percent / hexane; tetrahydrofuran / 0.5 h / -78 °C
2.1: 31.4 percent / H2N-NH2*H2O / ethanol / Heating
View Scheme
参考文献
Ohta, Shunsaku; Tsuno, Naoki; Nakamura, Seikou; Taguchi, Norio; Yamashita, Masayuki; Kawasaki, Ikuo; Fujieda, Mieko
Heterocycles, 2000 , vol. 53, # 9 p. 1939 - 1955
