3-环己基-3-羟基-3-苯丙酸合成路线 （共 5 条）
反应条件
1: With sodium hydroxide; pig liver esterase in phosphate buffer
T=20°C; 27 h; ultrasound;
2: With hydrogenchloride in water
pH=1;
参考文献
Ribeiro, Carlos Magno R.; Passaroto, Elisa N.; Brenelli, Eugenia C.S.
Tetrahedron Letters, 2001 , vol. 42, # 37 p. 6477 - 6479
反应条件
1: 85 percent / Zn, I2 / dioxane / 3.25 h / 0 - 20 °C / Irradiation
2: 5.28 g / 15percent aq. KOH / 2.5 h / Heating
View Scheme
参考文献
Sjoe, Peter; Aasen, Arne Joergen
Acta Chemica Scandinavica, 1993 , vol. 47, # 5 p. 486 - 491
反应条件
1: cyclohexane; AlCl3 / -10 - 45 °C
2: magnesium; benzene
3: aq.-ethanolic KOH-solution
View Scheme
参考文献
Nenitzescu; Gavat
Chemische Berichte, 1937 , vol. 70, p. 1883,1885
反应条件
1: cyclohexane; AlCl3 / -10 - 45 °C
2: magnesium; benzene
3: aq.-ethanolic KOH-solution
View Scheme
参考文献
Nenitzescu; Gavat
Chemische Berichte, 1937 , vol. 70, p. 1883,1885
反应条件
potassium hydroxide; zinc
Multistep reaction;
参考文献
Schjelderup, Lise; Harbitz, Ole; Groth, Per; Aasen, Arne Joergen
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 5 p. 356 - 361
