3-羟基-6,6-二甲基-1-庚烯-4-炔合成路线 （共 14 条）
反应条件
hydrogen bromide; phosphorus tribromide; sodium carbonate
1.) EtOH, 2.) DMF, RT, overnight; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Stuetz, Anton; Petranyi, Gabor
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1539 - 1543
反应条件
hydrogen bromide; phosphorus tribromide
参考文献
Sandoz Ltd.
Patent: US4382951 A1, 1983 ;
反应条件
hydrogen bromide; phosphorus tribromide in ethanol
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Chou, Shan-Yen; Tseng, Chin-Lu; Chen, Shyh-Fong
Tetrahedron Letters, 2000 , vol. 41, # 20 p. 3895 - 3898
反应条件
boron trichloride in hexane
T=20°C; Chlorination; 0.166667 h; Product distribution; Further Variations:ReagentsTemperaturesreaction time;
参考文献
AUROBINDO PHARMA LTD
Patent: WO2007/52089 A1, 2007 ;
Location in patent: Page/Page column 7 ;
