4-氨基-1-(2-脱氧-2-氟-beta-D-阿拉伯呋喃糖基)-5-甲基-2(1H)-嘧啶酮合成路线 （共 5 条）
反应条件
ammonia; acetic acid 1.) reflux, 48 h, 2.) MeOH, 24 h; Yield given. Multistep reaction;
参考文献
Watanabe, Kyoichi A.; Su, Tsann-Long; Klein, Robert S.; Chu, Chung K.; Matsuda, Akira; et al.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 152 - 156
反应条件
ammonia in methanol
Ambient temperature; Yield given;
参考文献
Watanabe, Kyoichi A.; Su, Tsann-Long; Klein, Robert S.; Chu, Chung K.; Matsuda, Akira; et al.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 152 - 156
反应条件
1: (NH4)2SO4 / Heating
2: CH2Cl2 / 168 h / Ambient temperature
3: NH3 / methanol / Ambient temperature
View Scheme
参考文献
Watanabe, Kyoichi A.; Su, Tsann-Long; Klein, Robert S.; Chu, Chung K.; Matsuda, Akira; et al.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 152 - 156
反应条件
1: CH2Cl2 / 168 h / Ambient temperature
2: NH3 / methanol / Ambient temperature
View Scheme
参考文献
Watanabe, Kyoichi A.; Su, Tsann-Long; Klein, Robert S.; Chu, Chung K.; Matsuda, Akira; et al.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 152 - 156
反应条件
1: HBr gas / CH2Cl2 / 4 °C
2: CH2Cl2 / 168 h / Ambient temperature
3: NH3 / methanol / Ambient temperature
View Scheme
参考文献
Watanabe, Kyoichi A.; Su, Tsann-Long; Klein, Robert S.; Chu, Chung K.; Matsuda, Akira; et al.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 152 - 156
