1,3-二甲基-1H-吡唑-4-羧酸合成路线 （共 14 条）
反应条件
hydrogen; sodium carbonate; palladium on activated charcoal in water P=1520 Torr; Ambient temperature;
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: methylhydrazine; formic acid ethyl ester in ethanol T=0°C; Vilsmeier type formylation; 4 h; Reflux; 2: ethyl acetoacetate in ethanol 4 h; Reflux; 3: With sodium ethanolate in ethanol Knoevenagel type condensation; 0.75 h; Reflux; regioselective reaction;
参考文献
Tetrahedron Letters, , vol. 50, # 6 p. 696 - 699
反应条件
potassium permanganate in water
参考文献
Vasilevskii, S. F.; Gerasimov, V. A.; Shvartsberg, M. S.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 4 p. 683 - 685
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , # 4 p. 902 - 904
反应条件
1: 72 percent / triethylamine / benzene 2: 29 percent / phosphoryl chloride / 2 h / Heating 3: 92 percent / NaOH / ethanol; H2O / 2 h / Heating 4: 93 percent / sodium carbonate, H2 / 5percent Pd/C / H2O / 1520 Torr / Ambient temperature View Scheme
参考文献
Australian Journal of Chemistry, , vol. 36, # 1 p. 135 - 147
反应条件
1: 29 percent / phosphoryl chloride / 2 h / Heating 2: 92 percent / NaOH / ethanol; H2O / 2 h / Heating 3: 93 percent / sodium carbonate, H2 / 5percent Pd/C / H2O / 1520 Torr / Ambient temperature View Scheme
参考文献
Australian Journal of Chemistry, , vol. 36, # 1 p. 135 - 147
反应条件
1: 92 percent / NaOH / ethanol; H2O / 2 h / Heating 2: 93 percent / sodium carbonate, H2 / 5percent Pd/C / H2O / 1520 Torr / Ambient temperature View Scheme
参考文献
Australian Journal of Chemistry, , vol. 36, # 1 p. 135 - 147
反应条件
1: 94 percent / sodium carbonate, KMnO4 / H2O / 1 h / 60 °C 2: 93 percent / sodium carbonate, H2 / 5percent Pd/C / H2O / 1520 Torr / Ambient temperature View Scheme
参考文献
Australian Journal of Chemistry, , vol. 36, # 1 p. 135 - 147
反应条件
sodium hydroxide in water T=70°C; Electrochemical reaction;
参考文献
Russian Chemical Bulletin, , vol. 61, # 6 p. 1148 - 1153
Izv. Akad. Nauk, Ser. Khim., , vol. 61, # 6 p. 1139 - 1143,5
反应条件
hydrogenchloride in water 24 h; Heating;
参考文献
Bajnati, Abdelilah; Hubert-Habart, Michel
Bulletin de la Societe Chimique de France, 1988 , # 3 p. 540 - 547
参考文献
EP1176140 A1, ;
Page 45 ;
