(4-氯苯乙炔基)三甲基硅烷合成路线 （共 20 条）
反应条件
4-(MeOPEG2000OCH2)C6H4CH2P(1-Ad)2*HBr; diisopropylamine; sodium tetrachloropalladium (II); copper(l) iodide in n-heptane; dimethyl sulfoxide T=60°C; Sonogashira coupling; 3 h;
参考文献
Koellhofer, Axel; Plenio, Herbert
Chemistry - A European Journal, 2003 , vol. 9, # 6 p. 1416 - 1425
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide in triethylamine 2 h; Ambient temperature;
参考文献
Morris; Wishka
Synthesis, 1994 , # 1 p. 43 - 46
反应条件
proton-exchanged montmorillonite in 1,4-dioxane T=100°C; 3 h; Inert atmosphere;
参考文献
Motokura, Ken; Matsunaga, Shigekazu; Miyaji, Akimitsu; Yashima, Tatsuaki; Baba, Toshihide
Tetrahedron Letters, 2011 , vol. 52, # 50 p. 6687 - 6692
反应条件
1: ZTK-2-124 With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: chloro-trimethyl-silane in tetrahydrofuran; hexane T=-78°C; 1 h;
参考文献
Araki, Yuta; Kobayashi, Koji; Yonemoto, Misato; Kondo, Yoshinori
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 1 p. 78 - 80
反应条件
diphenylphosphine-based palladium(0) complex on MCM-41 in water; N,N-dimethyl-formamide T=60°C; Stille coupling; 6 h;
参考文献
Zhao, Hong; Wang, Yue; Sha, Junchao; Sheng, Shouri; Cai, Mingzhong
Tetrahedron, 2008 , vol. 64, # 32 p. 7517 - 7523
反应条件
tetrabutylammomium bromide; palladium dichloride in 1-methyl-pyrrolidin-2-one T=100°C; 7 h; Title compound not separated from byproducts;
参考文献
Advanced Synthesis and Catalysis, , vol. 348, # 14 p. 1874 - 1882
反应条件
1: ZTK-2-124 With n-butyllithium in tetrahydrofuran; hexane T=-10°C; 0.333333 h; 2: With copper(l) iodide in tetrahydrofuran; hexane T=-10°C; 1 h; 3: trimethylsilyl iodide in tetrahydrofuran; hexane T=-78°C; 0.0833333 h;
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 44 p. 7260 - 7263
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran 7 h; Heating;
参考文献
Gelman, Dmitri; Tsvelikhovsky, Dmitry; Molander, Gary A.; Blum, Jochanan
Journal of Organic Chemistry, 2002 , vol. 67, # 18 p. 6287 - 6290
反应条件
1.1: PPh3 / CH2Cl2 / 0.08 h / 0 °C 1.2: CH2Cl2 / 0.33 h / 0 °C 2.1: n-BuLi / hexane; tetrahydrofuran / 0.33 h / -10 °C 2.2: CuI / tetrahydrofuran; hexane / 1 h / -10 °C 2.3: tetrahydrofuran; hexane / 0.08 h / -78 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 44 p. 7260 - 7263
反应条件
tetrakis(triphenylphosphine) palladium(0)
参考文献
Journal of the American Chemical Society, , vol. 108, p. 3402
