4-[2-(3,4-二氯苯基)-1,3-噻唑-4-基]-5-羟基-1H-吡咯-2,3-二酮合成路线 （共 3 条）
反应条件
potassium tert-butylate in N,N-dimethyl-formamide
Ambient temperature;
参考文献
Rooney; Randall; Streeter; Ziegler; Cragoe Jr.; Schwam; Michelson; Williams; Eichler; Duggan; Ulm; Noll
Journal of Medicinal Chemistry, 1983 , vol. 26, # 5 p. 700 - 714
反应条件
1: 72 percent / ethanol / 4 h / Heating
2: 85 percent / NH4OH / dioxane / 120 h / Ambient temperature
3: 56 percent / t-BuOK / dimethylformamide / Ambient temperature
View Scheme
参考文献
Rooney; Randall; Streeter; Ziegler; Cragoe Jr.; Schwam; Michelson; Williams; Eichler; Duggan; Ulm; Noll
Journal of Medicinal Chemistry, 1983 , vol. 26, # 5 p. 700 - 714
反应条件
1: 85 percent / NH4OH / dioxane / 120 h / Ambient temperature
2: 56 percent / t-BuOK / dimethylformamide / Ambient temperature
View Scheme
参考文献
Rooney; Randall; Streeter; Ziegler; Cragoe Jr.; Schwam; Michelson; Williams; Eichler; Duggan; Ulm; Noll
Journal of Medicinal Chemistry, 1983 , vol. 26, # 5 p. 700 - 714
