N-[(1R)-2-羟基-1-苯基乙基]-乙酰胺合成路线 (共 12 条)
反应条件
lithium hydroxide; K2lt;OsO2(OH)4gt;; 1,4-bis(9-O-dihydroquinidine)phthalazine in propan-1-ol
T=4°C; 20 h; other solvent, ligand; Product distribution;
参考文献
Bruncko, Milan; Schlingloff, Gunther; Barry Sharpless
Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 13-14 p. 1483 - 1486
反应条件
1: N,N'-Carbonyldiimidazol / toluene / 48 h / Ambient temperature
2: 7.3 mg / 3.5 N H2SO4 / dioxane / 2 h / Heating
3: 7.3 mg / H2 / Pd/C / methanol / 2 h / 1520 Torr
View Scheme
参考文献
Santoso, Sentot; Kemmer, Thorsten; Trowitzsch, Wolfram
Liebigs Annalen der Chemie, 1981 , # 4 p. 642 - 657