(11alpha,16alpha)-11,17,21-三羟基-16-甲基孕甾-1,4-二烯-3,20-二酮合成路线 （共 3 条）
反应条件
3: sodium acetate; acetic acid 4: N-bromo-acetamide; dichloromethane; tert-butyl alcohol / Reagens 4: wss. Perchlorsaeure, Erwaermen des Reaktionsprodukts mit Kaliumacetat in Aceton View Scheme
参考文献
Oliveto et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 4431
反应条件
3: sodium acetate; acetic acid 4: N-bromo-acetamide; dichloromethane; tert-butyl alcohol / Reagens 4: wss. Perchlorsaeure, Erwaermen des Reaktionsprodukts mit Kaliumacetat in Aceton 5: CHCl3; THF; HF View Scheme
参考文献
Oliveto et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 4431
反应条件
1: triethylamine / dichloromethane / -15 °C 2: phosphorus pentachloride / tetrahydrofuran / -85 °C 3: perchloric acid; 1,3-dibromo-5,5-dimethyl-hydantoin / water; N,N-dimethyl-formamide / 1 h / 20 °C 4: sodium hydroxide / dichloromethane; methanol / 0 - 5 °C View Scheme
参考文献
Fu, Xiaoyong; Tann, Chou-Hong; Thiruvengadam
Organic Process Research and Development, 2001 , vol. 5, # 4 p. 376 - 382
