((4-((4-甲氧基苯基)乙炔)苯基)乙炔)三甲基硅烷合成路线 （共 4 条）
反应条件
potassium carbonate in tetrahydrofuran; methanol T=20°C;
参考文献
Ding, Changhua; Babu, Govindarajulu; Orita, Akihiro; Hirate, Takayoshi; Otera, Junzo
Synlett, 2007 , # 16 p. 2559 - 2563
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in tetrahydrofuran
T=25°C; Sonogashira coupling reaction;
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
1.2: KOH / methanol; tetrahydrofuran / 25 °C
2.1: 89 percent / Pd(PPh3)2Cl2; Et2NH; CuI / tetrahydrofuran / 25 °C
View Scheme
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
1.1: lithium hexamethyldisilazide / tetrahydrofuran / -78 °C
1.2: tetrahydrofuran
2.1: ClP(O)(OEt)2 / tetrahydrofuran / 20 °C
2.2: lithium hexamethyldisilazide / tetrahydrofuran / 30 °C
View Scheme
参考文献
Ding, Changhua; Babu, Govindarajulu; Orita, Akihiro; Hirate, Takayoshi; Otera, Junzo
Synlett, 2007 , # 16 p. 2559 - 2563
