ammonia in methanol 1.5 h; Ambient temperature;

1: DCC / CH2Cl2 / 16 h / Ambient temperature 2: 66 percent / TFA / various solvent(s) / 1.5 h / Ambient temperature 3: 90 percent / NH3 / methanol / 1.5 h / Ambient temperature View Scheme

1: Et3N / ethanol / Ambient temperature 2: DCC / CH2Cl2 / 16 h / Ambient temperature 3: 66 percent / TFA / various solvent(s) / 1.5 h / Ambient temperature 4: 90 percent / NH3 / methanol / 1.5 h / Ambient temperature View Scheme

1: 66 percent / TFA / various solvent(s) / 1.5 h / Ambient temperature 2: 90 percent / NH3 / methanol / 1.5 h / Ambient temperature View Scheme

1: K2CO3 / CH2Cl2 / 2 h / Heating 2: 2.08 N aq. KOH / methanol / 2 h / Ambient temperature View Scheme