反式-2-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)苯乙烯合成路线 （共 15 条）
反应条件
1: With 6-di-tert-butylphosphinomethyl-2,2'-bipyridine in toluene
0.0166667 h; Inert atmosphereGloveboxSchlenk technique;
2: With NaBEt3H in toluene
T=25°C; 0.5 h; Inert atmosphereGloveboxSchlenk technique;
参考文献
Zhang, Lei; Peng, Dongjie; Leng, Xuebing; Huang, Zheng
Angewandte Chemie - International Edition, 2013 , vol. 52, # 13 p. 3676 - 3680
Angew. Chem., 2013 , vol. 52, # 13 p. 3676 - 3680,5
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium in toluene
T=20°C; 24 h; Product distribution; Further Variations:ReagentsSolvents;
参考文献
Yamamoto, Yasunori; Fujikawa, Rhyou; Umemoto, Tomokazu; Miyaura, Norio
Tetrahedron, 2004 , vol. 60, # 47 p. 10695 - 10700
反应条件
(iPrPNN)FeCl2; NaBEt3H in tetrahydrofuran; toluene
T=25°C; 1 h; Inert atmosphereGloveboxSchlenk technique; chemoselective reaction;
参考文献
Zhang, Lei; Zuo, Ziqing; Leng, Xuebing; Huang, Zheng
Angewandte Chemie - International Edition, 2014 , vol. 53, # 10 p. 2696 - 2700
Angew. Chem., 2014 , vol. 126, # 10 p. 2734 - 2738,5
反应条件
methyl iodide
under Ar or N2, heating; not isolated, detected by NMR;
参考文献
Matteson, Donald S.; Arne, Karl H.
Organometallics, 1982 , vol. 1, p. 280 - 288
反应条件
1.1: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / ethylene glycol dimethyl ether; water / 1 h / Heating / reflux
2.1: sodium hydroxide; ethanol; water / 0.5 h / 80 °C
2.2: 0 - 20 °C
View Scheme
参考文献
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
Patent: US2008/153802 A1, 2008 ;
